Extended Liver Screen

£99.00

We offer a comprehensive assessment of your liver function, including basic liver screen as well as your lipid metabolism, glycaemic control, vitamin levels to help diagnose liver dysfunction or underlying metabolic disorders which could lead to liver disease.

SKU: RD003 Category:

Description

The liver is a complex organ which produces proteins and enzymes, blood clotting factors, bile and stores vitamins. Our liver function test can detect liver disease by measuring specific enzymes in the blood (ALT, ALP, GGT), albumin – the main protein made by the liver, bilirubin – a substance made during the breakdown of red blood cells. Liver function tests may be useful if you are concerned about high alcohol intake, have a family history of liver disease, fatty liver, or are showing symptoms of a liver condition.
We offer a comprehensive assessment of your liver function, including basic liver screen as well as your lipid metabolism, glycaemic control, vitamin levels to help diagnose liver dysfunction or underlying metabolic disorders which could lead to liver disease.

  • Alanine Aminotransferase (ALT)
    Alanine Aminotransferase (ALT) is an enzyme mainly found in the liver, playing a significant role in the metabolism of proteins. ALT is used as a key indicator of liver health. Elevated levels of ALT in the blood often signify liver damage or inflammation, as it is released into the bloodstream when liver cells are injured. Common causes of increased ALT levels include viral hepatitis, fatty liver disease, and alcohol-related liver damage. It's frequently measured alongside other liver enzymes in blood tests to diagnose and monitor liver conditions. Low levels of ALT are typically not a concern and do not usually indicate any specific health issue.

  • Albumin
    Albumin is the most abundant protein in the blood plasma, produced by the liver. It plays a vital role in maintaining the osmotic pressure needed for proper distribution of bodily fluids between blood vessels and body tissues. Additionally, albumin serves as a carrier protein for various substances including hormones, vitamins, and drugs. Measuring albumin levels is important for assessing liver and kidney function, as well as nutritional status. Low albumin levels can indicate liver disease, kidney disease, malnutrition, or inflammatory diseases. High albumin levels are less common and can be due to dehydration or high protein intake.

  • Alkaline Phosphatase (ALP)
    Alkaline Phosphatase (ALP) is an enzyme found throughout the body, but primarily in the liver, bones, kidneys, and digestive system. It plays a key role in breaking down proteins and is important in the process of dephosphorylation. ALP levels are often measured as part of routine blood tests to assess liver and bone health. Elevated levels can indicate liver disease, bile duct obstruction, bone disorders, or certain cancers. In contrast, low ALP levels are less common but can occur in malnutrition, certain deficiencies, or genetic disorders.

  • Basophils
    These cells play a role in allergic responses. Elevated levels can be seen in allergies, chronic inflammation, and certain blood disorders.

  • Chol:HDL Ratio
    The Cholesterol to High-Density Lipoprotein (Chol:HDL) ratio is a calculation derived from dividing the total cholesterol by the HDL cholesterol level. This ratio is used as an indicator of cardiovascular risk. • High Ratio: A higher Chol:HDL ratio indicates a higher risk of heart disease. It suggests that there is a greater proportion of cholesterol in relation to the "good" HDL cholesterol, which is protective against heart disease. Generally, a ratio above 5.0 is considered high risk. • Low Ratio: A lower ratio is more desirable and indicates a lower risk of heart disease. It reflects a higher proportion of HDL cholesterol relative to total cholesterol. A ratio below 3.5 is usually considered optimal.

  • Cholesterol
    Cholesterol is a waxy, fat-like substance found in all cells of the body, necessary for making hormones, vitamin D, and substances that help digest foods. The body produces cholesterol, but it is also obtained from animal-based foods. Cholesterol travels in the blood in packages called lipoproteins, which include low-density lipoprotein (LDL, or "bad" cholesterol) and high-density lipoprotein (HDL, or "good" cholesterol). High levels of LDL cholesterol can lead to plaque build-up in arteries, increasing the risk of heart disease and stroke. Conversely, high levels of HDL cholesterol are considered protective as they help transport cholesterol away from artery walls. Regular monitoring of cholesterol levels through blood tests is key for assessing cardiovascular risk and guiding dietary and lifestyle interventions or medication management to maintain heart health.

  • Eosinophils
    Eosinophils are a type of white blood cell that play a key role in the body's immune response, particularly in fighting parasitic infections and in allergic reactions. They are part of the body's immune system and are produced in the bone marrow. Eosinophils can be measured through a blood test, often as part of a complete blood count (CBC).
    • High Levels of Eosinophils (Eosinophilia): Can indicate allergic reactions, parasitic infections, autoimmune diseases, and certain types of leukemia or other health conditions.
    • Low Levels of Eosinophils: Generally not a concern and can occur with the use of certain medications, like corticosteroids, or during acute infections.

  • Folic acid (Folate)
    Folic acid, also known as folate or vitamin B9, is a crucial nutrient involved in the formation of red blood cells and the synthesis of DNA, making it essential for healthy cell growth and function. High Folic Acid Levels: Typically not a concern; may occur with supplementation or a diet rich in folate. Rarely, high levels could mask vitamin B12 deficiency. Low Folic Acid Levels: Indicate a deficiency, which can lead to health issues such as anaemia (particularly megaloblastic anaemia), birth defects during pregnancy (like neural tube defects), and impaired cell growth. Folate deficiency can be caused by inadequate dietary intake, certain medications, alcoholism, or malabsorption disorders.

  • Gamma-Glutamyl Transferase (GGT)
    Gamma-Glutamyl Transferase (GGT) is an enzyme that primarily exists in the liver. It plays a crucial role in the metabolism of glutathione and the transfer of amino acids and peptides across the cellular membrane. GGT is often measured in blood tests as a marker of liver health. Elevated levels of GGT are commonly associated with liver diseases, such as hepatitis, cirrhosis, and liver damage due to alcohol or drug use. It can also indicate bile duct problems. Because GGT levels increase with alcohol consumption and certain medications, it is also used to monitor alcohol abuse and adherence to certain medications. Low levels of GGT are generally not a concern and are less commonly noted in clinical practice.

  • Globulin
    Globulin is a group of proteins in the blood, playing diverse roles in immune response, blood clotting, and transport of various substances like hormones and vitamins. There are several types of globulins, including alpha, beta, and gamma globulins. Gamma globulins are primarily antibodies, which are crucial for immune defense. Globulin levels are measured as part of a total protein test and can also be assessed through the serum protein electrophoresis test. Abnormal globulin levels can indicate a range of conditions, including immune disorders, liver or kidney disease, nutritional problems, and certain infections or cancers. High levels may be seen in chronic inflammatory diseases or infections, while low levels may indicate immune deficiencies or liver damage.

  • HDL Cholesterol
    HDL Cholesterol (High-Density Lipoprotein) known as "good" cholesterol, helps remove other forms of cholesterol from your bloodstream. Higher levels of HDL cholesterol are associated with a lower risk of heart disease. • High Levels: Higher levels of HDL cholesterol are considered protective against heart disease. • Low Levels: Low levels of HDL cholesterol increase the risk of heart disease. Low HDL can be a result of genetic factors, type 2 diabetes, smoking, being overweight, and a sedentary lifestyle.

  • Haematocrit (Hct)
    This assesses the percentage of blood volume composed of red blood cells. It helps diagnose and monitor conditions like anaemia, polycythaemia, and hydration status.

  • Haemoglobin (Hb)
    Haemoglobin (Hb) is a vital protein in red blood cells responsible for transporting oxygen from the lungs to the rest of the body and returning carbon dioxide from the tissues back to the lungs. It gives red blood cells their characteristic color and is essential for cellular respiration.
    • High Haemoglobin Levels: Elevated levels can occur in conditions like polycythemia vera, chronic lung disease and smoking, dehydration, or living at high altitudes.
    • Low Haemoglobin Levels: Low levels are indicative of anaemia, which can result from a variety of causes including iron deficiency, chronic diseases, blood loss, or bone marrow problems.

  • HbA1C
    One of the key tests in the diagnosis of diabetes - Haemoglobin A1C (HbA1C) is a blood test that measures the average level of blood sugar (glucose) over the past two to three months. It does this by calculating the percentage of haemoglobin, the protein in red blood cells that carries oxygen, which is coated with sugar (glycated). High HbA1C Levels: Indicate poor blood sugar control and a higher risk of diabetes complications. Elevated levels are used to diagnose type 2 diabetes and prediabetes, and to monitor diabetes management. Low HbA1C Levels: Generally seen in individuals without diabetes or with well-controlled diabetes. Very low levels may suggest hypoglycemia, particularly in diabetic patients using insulin or certain diabetes medications.

  • LDL Cholesterol
    LDL Cholesterol  (Low-Density Lipoprotein), often referred to as "bad" cholesterol, is a type of cholesterol that can accumulate in the walls of blood vessels, leading to atherosclerosis and increasing the risk of heart disease and stroke. • High Levels: Elevated LDL levels are a major risk factor for coronary artery disease. Levels above 3 mmol/L are generally considered high, but the target level can vary based on individual heart disease risk factors. • Low Levels: Lower LDL cholesterol is generally better for heart health. However, extremely low levels should be discussed with a healthcare provider, as they might be a sign of other health issues.

  • Lymphocytes
    These cells are vital in the immune response against viral infections. Abnormal levels can indicate viral infections, lymphoma, or immune disorders.

  • Mean Cell Haemoglobin (MCH)
    Measures the average haemoglobin content in an individual red blood cell. It's useful in diagnosing the type of anaemia.

  • Mean Cell Haemoglobin Concentration (MCHC)
    This test measures the concentration of haemoglobin in a given volume of red cells, aiding in distinguishing between different types of anaemia.

  • Mean Cell Volume (MCV)
    Indicates the average size of red blood cells. It helps in classifying anaemias as microcytic, normocytic, or macrocytic. • High MCV indicates macrocytic anaemia, often due to Vitamin B12 or folate deficiency. • Low MCV suggests microcytic anaemia, commonly due to iron deficiency.

  • Mean Platelet Volume (MPV)
    Provides information about platelet production in bone marrow and can indicate risks for diseases like heart disease or thrombosis.

  • Monocytes
    A type of white cell involved in fighting certain infections and helping other white blood cells remove dead or damaged tissues.

  • Neutrophils
    A subtype of white blood cell, crucial in fighting bacterial infections. Abnormal levels can indicate bacterial infections, stress, or bone marrow disorders.

  • Non-HDL Cholesterol
    Non-HDL cholesterol is calculated by subtracting the HDL cholesterol from the total cholesterol. It represents all the "bad" types of cholesterol, including LDL (Low-Density Lipoprotein) and VLDL (Very Low-Density Lipoprotein), which are associated with the buildup of plaque in the arteries and an increased risk of cardiovascular disease. • High Levels: Elevated non-HDL cholesterol levels indicate a higher risk of developing heart disease and stroke. It suggests an accumulation of cholesterol in the arteries. The ideal level for non-HDL cholesterol depends on individual risk factors, but generally, a level below 4 mmol/L is considered normal. • Low Levels: Lower non-HDL cholesterol levels are usually considered beneficial and suggest a lower risk of heart disease. However, extremely low levels should be evaluated by a healthcare provider to rule out any underlying health issues.

  • Platelets
    Essential for blood clotting. The test can diagnose or monitor bleeding disorders, thrombocytopenia, or thrombocythemia.

  • Red Blood Cells (RBC)
    Measures the number of red blood cells, which are vital for transporting oxygen throughout the body. An abnormal count can indicate conditions like anaemia, dehydration, or bone marrow disorders. • High levels can indicate polycythaemia vera or dehydration. • Low levels suggest anaemia or haemorrhage.

  • Red Cell Distribution Width (RDW)
    Assesses the variation in red blood cell size, which can help in diagnosing specific types of anaemia.

  • Total Bilirubin
    Total bilirubin is a compound produced during the breakdown of red blood cells in the body. It is transported through the bloodstream to the liver, where it undergoes further processing and is eventually excreted from the body through bile. Bilirubin plays a crucial role in the metabolism of heme, a component of hemoglobin found in red blood cells. Elevated levels of total bilirubin in the blood may indicate liver dysfunction, bile duct obstruction, or excessive breakdown of red blood cells, which can occur due to various conditions such as liver disease, hepatitis, gallstones, or hemolytic anemia.

  • Total Protein
    Provides information about the total amount of albumin and globulin in the blood. Abnormal levels can suggest a variety of conditions including liver and kidney disorders, nutritional problems, and chronic diseases.

  • Triglycerides
    Triglycerides are a type of fat found in the blood. When you eat, your body converts any calories it doesn't need to use right away into triglycerides, which are stored in fat cells. • High Levels: High triglyceride levels can increase the risk of coronary artery disease. Elevated levels can be due to overweight/obesity, physical inactivity, cigarette smoking, excess alcohol consumption, a very high carbohydrate diet, certain diseases and medications, and genetic disorders. • Low Levels: Low triglyceride levels are generally not a concern and are typically seen as beneficial. However, extremely low levels can be a result of malnutrition, malabsorption, or hyperthyroidism.

  • Vitamin B12
    Vitamin B12, also known as cobalamin, is a vital nutrient that plays a key role in nerve function, red blood cell production, and DNA synthesis. It's essential for maintaining healthy nerve cells and is crucial in the formation of DNA and RNA. High Vitamin B12 Levels: While not commonly a concern, abnormally high levels can be associated with certain medical conditions, including liver disease, kidney failure, or certain types of leukaemia. Low Vitamin B12 Levels: Indicate a deficiency, which can lead to serious health issues, such as pernicious anaemia, neurological problems, and cognitive impairments. Causes of B12 deficiency include inadequate dietary intake (common in vegetarians and vegans), malabsorption disorders, certain medications, and intrinsic factor deficiency.

  • White Blood Cells (WBC)
    This count measures the body's immune cells. Abnormal counts can indicate infections, inflammatory diseases, and hematologic conditions.

How it Works
1

Choose one of our test packages according to your needs – whether this would be general health screening, nutritional state, sexual health or monitoring of a chronic condition and get it delivered to your home or office.

2

Perform the test at your comfort zone. This will require a fingerprick, swab of urine sample collection. Instructions will be included in your kit. Post it back to one of our accredited laboratories in a prepaid envelope.

3

We will notify you when results are available and you can access it in your dashboard together with advice from our health experts. Repeat tests as recommended and track results to keep your health in a good shape all the time.

Video tutorial

This video shows step-by-step guidance on how to use The Red Drop blood collection kits